Citicort is an anti-inflammatory glucocorticoid that contains hydrocortisone sodium succinate as the active ingredient . It is used to control symptoms caused by sudden low levels of corticosteroids in the body. It is also used to decrease inflammation. This can help to control a wide variety of disease states, characterized by excessive inflammation.
- To treat or prevent allergic reactions.
- As treatment of certain kinds of autoimmune diseases, skin conditions, asthma and other lung conditions.
- As treatment for a variety of cancers, such as leukemia, lymphoma, and multiple myeloma.
- To treat nausea and vomiting associated with some chemotherapy drugs.
- Used to stimulate appetite in cancer patients with severe appetite problems.
- The lotion (topical) is used in treatment of allergic skin reactions, and relieves symptoms of itching, redness, and swelling.
- Also used to replace steroids in conditions of adrenal insufficiency (low production of needed steroids produced by the adrenal glands).
- As an anti-inflammatory medication
- In adults:100 to 500mg hydrocortisone (1 to 5ml) administered by slow intravenous injection, taking at least half to one minute. This dose can be repeated three or four times in 24 hours.
- In children:As a guide, infants up to 1 year may be given 25mg hydrocortisone intravenously; children 1 to 5 years, 50mg; 6 to 12 years, 100mg (1ml). This dose can be repeated three or four times in 24 hours.
It works as an ant iinflammatory and by immune suppression
Hydrocortisone is a glucocorticoid with anti-inflammatory properties.
Absorption & Distribution
Hydrocortisone is readily absorbed from the gastrointestinal tract and peak blood concentrations are attained in about an hour. It is more than 90% bound to plasma proteins.
Hydrocortisone is metabolized in the liver and most body tissues to hydrogenated and degradated forms such as tetrahydrocortisone and tetrahydrocortisol.
These are then excreted in the urine, mainly conjugated as glucuronides, together with a very small proportion of unchanged hydrocortisone.
- Hydrocortisone sodium succinate is contraindicated in systemic fungal infections and patients with known hypersensitivity to the product and its constituents.
- Intramuscular corticosteroid preparations are contraindicated for idiopathic thrombocytopenic purpura.
- Do not take aspirin, or products containing aspirin unless your doctor specifically permits this.
- Do not receive any kind of immunization or vaccination without your doctor’s approval while taking Hydrocortisone Sodium Succinate.
- If you have been on hydrocortisone pills daily, for a long period of time, serious side effects may occur if you discontinue the medication abruptly. Do not stop taking this medication unless directed by your healthcare provider. Do not change the dose of hydrocortisone on your own.
- Inform your health care professional if you are pregnant or may be pregnant prior to starting this treatment. Pregnancy category C (use in pregnancy only when benefit to the mother outweighs risk to the fetus).
- For both men and women: Do not conceive a child (get pregnant) while taking hydrocortisone
- Do not breast feed while taking this medication.