Zarazone SB 10002018-12-08T09:13:54+00:00
Zarazone-SB-1-gm-injection

Zarazone SB injection is a combination of cefoparazone and sulbactum. Cefoparazone is a third generation antibiotic which is effective in treatment of pseudomonas bacterial infections.

Sulbactum is a beta-lactum inhibitor which inhibits beta-lactamase enzyme produced by the bacteria to protect from antibiotics.

  • Skin and soft tissue infections
  • Meningitis
  • Respiratory tract infections
  • Intra-abdominal infections
  • Urinary tract infections
  • Septicaemia
  • Bone and joint infections
  • Gynaecological infections

1-2 g daily, given in equally divided doses every 12 hours. 

Cefoperazone causes inhibition of bacterial cell wall synthesis of actively dividing cells by binding to penicillin binding proteins. Sulbactum causes irreversible inactivation of beta-lactamases

Absorption

After 1gm IV administration the serum concentration is obtained in 30min. The average peak plasma concentration achieved in 5mins.

Distribution

The plasma protein binding of cefoperazone is 82-93% and sulbactum is 38%

Excretion

Cefoperzone is excreted in urine mainly in bile. Sulbactum is excreted in urine during initial eight hours of administration

  • Allergy to penicillin
  • Hypersensitive reaction to any ingredient present
  • Serious and fatal reactions
  • With prolonged use, overgrowth of susceptible organism may occur
Send Enquiry

We are glad that you preferred to contact us. Please fill our short form and one of our friendly team members will contact you back.

X
Send Enquiry WhatsApp chat